Histological reconstruction of cortical and nuclear infusion sites.

Cannula tip locations are shown for all subjects in each group on a series of 8 standard transverse sections at levels from −1.0 mm to −4.5 mm relative to skull lambda. For each subject in the five groups, two matching symbols indicates the location of the cortical and nuclear cannula tips. For example, one subject in the Cortex+Nucleus group has cannula positions indicated by filled circles – the cortical placement is seen at level −1.0 mm and the nuclear placement at level −3.0 mm. The scale bar indicates 5 mm. The separation of the two cannula tip locations may be judged by reference to distances in the rostro-caudal axis and transverse planes. Abbreviations: crI and crII - crus 1 and 2 (of ansiform lobe); DPFL - dorsal paraflocculus; FL - flocculus; HIV-V, HVI - hemispheral lobules 4–5 and 6 (of Larsell); ND - dentate nucleus; NF - fastigial nucleus; NI - interpositus nucleus; PM - paramedian lobe; VPFL - ventral paraflocculus; II-X vermis lobules 2–10 (of Larsell).