Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate

Crystal structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS) in complex with indole glycerol phosphate (IGP) amd anthranilate Descriptor: 2-AMINOBENZOIC ACID, INDOLE-3-GLYCEROL PHOSPHATE, Indole-3-glycerol phosphate synthase Authors: Reddy, M.C.M, Bruning, J.B, Thurman, C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) Deposit date: 2011-07-25 Release date: 2012-08-08 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis To be Published

结核分枝杆菌（Mycobacterium tuberculosis）吲哚甘油磷酸合酶（Indole Glycerol Phosphate Synthase，IGPS）与吲哚甘油磷酸（indole glycerol phosphate，IGP）及邻氨基苯甲酸（anthranilate）结合的晶体结构。数据集描述：2-氨基苯甲酸（2-AMINOBENZOIC ACID）、吲哚-3-甘油磷酸（INDOLE-3-GLYCEROL PHOSPHATE）、吲哚-3-甘油磷酸合酶。作者：Reddy, M.C.M、Bruning, J.B、Thurman, C、Sacchettini, J.C、结核分枝杆菌结构基因组学联盟（TB Structural Genomics Consortium，TBSGC）。提交日期：2011-07-25，发布日期：2012-08-08，最后修改日期：2023-11-15。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.6 Å。引用文献：《结核分枝杆菌吲哚甘油磷酸合酶（IGPS）的结构解析与抑制：色氨酸生物合成的关键酶》（Structural Insights and Inhibition of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS): an Essential Enzyme for Tryptophan Biosynthesis），待发表。