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Articular Fibrocartilage-Targeted Therapy by Microtubule Stabilization

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE207148
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To investigate the fibrotic effect on BMSCs by CTGF and TGFβ1 treatment, and the anti-fibrotic effect of docetaxel on fibrotic chondrocytes. We established BMSCs primary culture and treated CTGF and TGFβ1, then treated by docetaxel. Comparative gene expression profiling analysis of RNA-seq data for control Bone marrow-mesenchymal stem cells (BMSCs) and fibrotic BMSCs (treated with CTGF and TGF-β1), induced fibrotic-chondrocytes (iFCs)and iFCs treated with docetaxel
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2022-11-23
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