Effect of competitive interactions between pairs of TFs on the accuracy of modeling ChIP data.

STAP was used with two motifs – the primary motif and a secondary motif (“Motif 2”), but with no interaction between binding sites considered. Thus the only influence of Motif 2 on predicted occupancy of the primary TF is due to overlapping sites. Shown are all cases in which both improvements were more than 0.04, P-value≤0.05 and Z-score ≥3. The column “ImprOverM2” is the difference between CC(M1+M2) and the absolute value of CC(M2).