Chronic psoriatic skin inflammation leads to increased monocyte adhesion and aggregation

ChEBI2015-06-27 更新2026-07-12 收录

银屑病病理

单核细胞行为研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70327 数据链接链接失效反馈

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Chronic psoriatic skin inflammation leads to increased monocyte adhesion and aggregation

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2015-06-27

Single Cell and Spatial Sequencing Characterizes Cell Type Composition and Cell-Cell Interaction in Psoriasis

银屑病病理

单细胞空间转录组学

The immunopathogenesis of psoriasis, a common chronic inflammatory disease of the skin, is still incompletely understood. Here we demonstrate, using a combination of single-cell and spatial-sequencing

NIAID Data Ecosystem140

Additional file 4: of Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

表观遗传学

银屑病病理

Total list of differentially methylated promoters. Hypo- and hypermethylated promoters are presented in two sheets. (XLSX 86 kb)

Figshare2018-08-10 更新80

Reconstituted human epidermis cultures treated with IL-1 family cytokines for 24 hours.. Homo sapiens

银屑病病理

IL-1细胞因子功能

Analysis of stratified epidermal cultures treated with IL-1a, IL-1F5, IL-1F6, IL-1F8 and IL-1F9 to determine the effects of these cytokines at 24h. Results provide insight into the role of IL-1 family

NIAID Data Ecosystem30

Activation of Unfolded Protein Response Pathways Promotes Keratinocyte Differentiation and Ameliorates Psoriasis Phenotypes

银屑病病理

角质形成细胞过程

In this study, we observed significant attenuation of UPR pathways specifically IRE1α-XBP1s and PERK signaling in psoriasis lesions. Administration of ER stress inducers (TM and BFA) alleviated psoria

NIAID Data Ecosystem80

Single Cell and Spatial Sequencing Define Processes by which Keratinocytes and Fibroblasts Amplify Inflammatory Responses in Psoriasis. Single Cell and Spatial Sequencing Define Processes by which Keratinocytes and Fibroblasts Amplify Inflammatory Responses in Psoriasis

银屑病病理

单细胞空间转录组学

The immunopathogenesis of psoriasis, a common chronic inflammatory disease of the skin, is incompletely understood. Here we demonstrate, using a combination of single cell and spatial RNA sequencing,

NIAID Data Ecosystem30

Chronic psoriatic skin inflammation leads to increased monocyte adhesion and aggregation

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