Mendeley supplemental

Mendeley supplemental table I. Reasons for the withdrawals. Mendeley supplemental table II. Adverse events of propranolol treatment. Mendeley supplemental table III. The effects of general characteristics and propranolol efficacy on relapse. Mendeley supplemental table IV. The effects of general characteristics and propranolol efficacy on major relapse. Supplemental figure 1. Images of typical lesion 1 evaluated through color Doppler ultrasound. (A) Lesion volume was 1.30 cm3 and blood flow grade was grade 3 before propranolol treatment. (B) Lesion volume was 0.42 cm3 and blood flow grade was grade 2 when reaching the maximum regression after 7 months of treatment. (C) Lesion volume was 0.37 cm3 and blood flow grade was grade 2 before propranolol withdrawal (after 3-month maintenance of treatment). (D) Four months after withdrawal, lesion volume was 1.32 cm3 and blood flow grade was grade 3, which was evaluated as a major relapse. Supplemental figure 2. Images of typical lesion 2 evaluated through color Doppler ultrasound. (A) Lesion volume was 13.85 cm3 and blood flow grade was grade 3 before propranolol treatment. (B) Lesion volume was 7.89 cm3 and blood flow grade was grade 1 when reaching the maximum regression after 4 months of treatment. (C) Lesion volume was 8.37 cm3 and blood flow grade was grade 1 before propranolol withdrawal (after 3-month maintenance of treatment). (D) Two months after withdrawal, lesion volume was 7.72 cm3 and blood flow grade was grade 1, which was evaluated as no relapse. Supplemental figure 3. Images of typical lesion 3 evaluated through color Doppler ultrasound. (A) Lesion volume was 15.00 cm3 and blood flow grade was grade 3 before propranolol treatment. (B) Lesion volume was 5.12 cm3 and blood flow grade was grade 1 when reaching the maximum regression after 4.3 months of treatment. (C) Lesion volume was 4.67 cm3 and blood flow grade was grade 1 before propranolol withdrawal (after 1-month maintenance of treatment). (D) Two months after withdrawal, lesion volume was 4.18 cm3 and blood flow grade was grade 1, which was evaluated as no relapse. Supplemental figure 4. Medication durations and ages at medication termination of patients with and without relapse, patients with and without major relapse.Mendeley补充表I：撤药原因 Mendeley补充表II：普萘洛尔（propranolol）治疗的不良事件 Mendeley补充表III：一般特征及普萘洛尔疗效对复发的影响 Mendeley补充表IV：一般特征及普萘洛尔疗效对严重复发的影响 补充图1：典型病灶1的彩色多普勒超声（color Doppler ultrasound）评估图像。(A) 普萘洛尔治疗前病灶体积为1.30 cm³，血流分级为3级。(B) 治疗7个月达最大消退时，病灶体积为0.42 cm³，血流分级为2级。(C) 普萘洛尔撤药前（维持治疗3个月后），病灶体积为0.37 cm³，血流分级为2级。(D) 撤药4个月后，病灶体积为1.32 cm³，血流分级为3级，评估为严重复发。 补充图2：典型病灶2的彩色多普勒超声评估图像。(A) 普萘洛尔治疗前病灶体积为13.85 cm³，血流分级为3级。(B) 治疗4个月达最大消退时，病灶体积为7.89 cm³，血流分级为1级。(C) 普萘洛尔撤药前（维持治疗3个月后），病灶体积为8.37 cm³，血流分级为1级。(D) 撤药2个月后，病灶体积为7.72 cm³，血流分级为1级，评估为无复发。 补充图3：典型病灶3的彩色多普勒超声评估图像。(A) 普萘洛尔治疗前病灶体积为15.00 cm³，血流分级为3级。(B) 治疗4.3个月达最大消退时，病灶体积为5.12 cm³，血流分级为1级。(C) 普萘洛尔撤药前（维持治疗1个月后），病灶体积为4.67 cm³，血流分级为1级。(D) 撤药2个月后，病灶体积为4.18 cm³，血流分级为1级，评估为无复发。 补充图4：伴复发与无复发患者、伴严重复发与无严重复发患者的用药时长及停药时年龄。