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Macrophage-produced VEGFC is induced by efferocytosis to resolve inflammation and improve ventricular function after myocardial infarction (RNA-Seq)

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NIAID Data Ecosystem2026-03-13 收录
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Recent reports have suggested a protective role for vascular endothelial growth factor C (VEGFC) during acute cardiac lymphangiogenesis post MI. Glinton et al. report that defective efferocytosis by macrophages after experimental MI leads to a reduction in cardiac lymphangiogenesis and Vegfc expression. Bulk mRNA sequencing 9 days post injury of cardiac extracts of Vegfcfl/fl versus Vegfcfl/fl;LysMCre mice subjected to coronary artery occlusion

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2022-06-30
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