RSC and Bud27 influences chromatin organization and alternative polyadenylation

The association of the RSC remodeler complex with the chromatin depends on the prefoldin-like Bud27 and determines the nucleosome positioning and polyadenylation sites usage in Saccharomyces cerevisiae在酿酒酵母（Saccharomyces cerevisiae）中，RSC重塑复合物（RSC remodeler complex）与染色质（chromatin）的结合依赖于预折叠蛋白（prefoldin）样Bud27，并决定了核小体定位（nucleosome positioning）与多聚腺苷酸化位点的使用。