Epigenetic Targeting of the Warburg Effect by Inhibition of Histone-Deacetylases Leads to Activation of Oxidative Metabolism
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https://www.ncbi.nlm.nih.gov/sra/SRP245630
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资源简介：
FDA-approved global (panobinostat, vorinostat) and selective (romidepsin) histone-deacetylase (HDAC) inhibitors elicit metabolic reprogramming in concert with disruption of several Warburg-effect related super-enhancers Overall design: U87 and NCH644 cells were treated with panobinostat or romidepsin for 24h. Thereafter, cells were harvested and subjected to CHIP isolation. DNA was subsequently processed for CHIP sequencing.
创建时间：
2020-04-30
