Rac1

ENCODES a protein that exhibits ATPase binding; GTP binding; GTPase activity; INVOLVED IN actin cytoskeleton organization; actin filament organization; bone resorption; PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; Arf family mediated signaling pathway; azathioprine pharmacodynamics pathway; ASSOCIATED WITH congestive heart failure; Left Ventricular Hypertrophy; autosomal dominant intellectual developmental disorder 48 (ortholog); FOUND IN cytosol; GABA-ergic synapse; Golgi membrane; INTERACTS WITH 11-deoxycorticosterone; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine

编码一种表现出ATPase结合、GTP结合、GTP酶活性、参与细胞骨架组织、肌动蛋白丝组织、骨吸收的蛋白质；参与Rho/Rac/Cdc42介导的信号通路、Arf家族介导的信号通路、巯嘌呤类药物药效学通路；与充血性心力衰竭、左心室肥厚、常染色体显性智力发育障碍48型（同源物）相关；存在于细胞质、GABA能突触、高尔基膜中；与11-去氧皮质酮、17β-雌二醇、2,3,7,8-四氯二苯并-对-二恶英相互作用。