Maresin 1 regulates inflammation in gingival mesenchymal stem cells under LPS-induced inflammatory states

Periodontitis is a chronic inflammatory condition marked by an imbalance between proinflammatory and proresolution mediators, which affects the tissues supporting the teeth. Maresin1 (MaR1) is a specialized pro-resolving lipid mediator (SPM) produced by macrophages, known for its role in regulating inflammatory processes. This study aimed to investigate the effects of MaR1 at varying concentrations on human gingival mesenchymal stem cells (hGMSCs) within inflammatory environments.