To understand the gene regulation of an organism of interest, a comprehensive genome annotation is essential. While some features, such as coding sequences, can be computationally predicted with high
One of the major mechanisms driving the evolution of all organisms is genomic rearrangement. In hyperthermophilic Archaea of the order Thermococcales, large chromosomal inversions occur so frequently
Additional file 6: Table S6. Metadata from metagenomes utilized in mapping to our archaeal MAGs (swine [62], human infant [64], human adult and palaeofaeces [63], mice [65], chicken [66], and cattle [
