Sequential C–H Functionalization Reactions for the Enantioselective Synthesis of Highly Functionalized 2,3-Dihydrobenzofurans
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The enantioselective synthesis of 2,3-dihydrobenzofurans was achieved by using two sequential C–H functionalization reactions, a rhodium-catalyzed enantioselective intermolecular C–H insertion followed by a palladium-catalyzed C–H activation/C–O cyclization. Further diversification of the 2,3-dihydrobenzofuran structures was possible by a subsequent palladium-catalyzed intermolecular Heck-type sp2 C–H functionalization.
创建时间：
2016-02-19
