Data for: Ulvan: a systematic review of extraction, composition and function

Abstract [Related publication] Species of green macroalgae (Chlorophyta) of the genus Ulva are edible seaweeds with a range of health promoting bioactive components. Ulva is high in dietary fibre which promotes gastrointestinal health and is linked to a reduction in the incidence of chronic diseases. The fundamental active constituent of Ulva is the soluble fibre ulvan, a gelling sulfated polysaccharide with biological activities including immunomodulating, antiviral, antioxidant, antihyperlipidemic and anticancer. Ulvan also has the capacity to modulate cellular signalling processes in both plant and animal systems leading to beneficial effects on productivity and health. Consequently, ulvan is of significant interest as a constituent in human health, agricultural, and biomaterial products. This comprehensive systematic review investigates and recommends acid extraction, ultrafiltration, sugar constituent and molecular weight analysis for the extraction, purification, and characterisation of ulvan, respectively. The biological activities of ulvans are then critically reviewed. Description of the data A meta-analysis of publications related to ulvan (a sulfated polysaccharide from green algae). Publications included were collected from Web of Science Core Collection and Scopus on 13/12/2017 using the search string: “(Ulvan* OR ((sulfate* OR sulphate*) AND polysaccharide* AND (Ulva OR Enteromorpha)))” Inclusion of a paper and data in a meta-table was subject to meeting the criteria stipulated by the search string. The paper must use algae from Ulva or Enteromorpha, and involve the extraction of sulfated polysaccharides. The paper must also contribute original quantitative data to the extraction procedure, characterisation and/or application of the sulfated polysaccharide. Each of the 154 publications included in the meta-analysis were read and data collected on: (1) the year, first author, first 40 characters of the title, journal of publication; (2) genera and species used along with country and a description of the biomass source; (3) The extractant applied, and concentration (if applicable), any enzymes applied, along with the temperature and duration of the extraction, and the precipitate if one was used; (4) the yield of polysaccharide (% DW), total carbohydrate, protein, ash, sulfate, uronic acid and neutral sugar content (in % w/w); (5) the average molecular weight; (6) the monosaccharide composition of rhamnose, uronic acids, glucuronic acid, xylose, iduronic acid, glucose and galactose (in % Mol, % DW, or Molar ratio); and (7) the tests applied to assess the biomedical application of the extracted polysaccharide. Data were recorded in the form and units that it was presented in unless the conversion was simply adjusting the magnitude of the value so that the data were comparable to other values in the table. If a conversion was performed, the cell is outlined in a dotted line and reading the formula will provide detail on the exact conversion applied. Some data were also estimated from figures, these values are also outlined in a dotted line. Where data were provided not in the units used in the table, these points were entered as text values with the corresponding units so as to avoid being included in the meta-analysis.【摘要【相关出版物】】 石莼属（Ulva）绿藻门（Chlorophyta）绿色大型藻类物种为可食用海藻，含有多种有益于健康的生物活性成分。石莼富含膳食纤维，可促进胃肠道健康，并与慢性病发病率降低相关。石莼的核心活性成分为可溶性纤维ulvan（Ulvan），这是一种具有凝胶特性的硫酸化多糖（sulfated polysaccharide），具备免疫调节、抗病毒、抗氧化、降血脂及抗肿瘤等多种生物活性。Ulvan还可调控植物与动物系统中的细胞信号通路（cellular signalling），进而对生物体的生产力与健康产生有益影响。因此，ulvan作为人类健康、农业及生物材料产品的成分受到广泛关注。本全面系统综述对ulvan的提取、纯化与表征方法进行了调研，并推荐采用酸提取、超滤（ultrafiltration）、糖组成及分子量分析分别用于其提取、纯化与表征流程。随后，本文对ulvan的生物活性进行了批判性综述。 【数据集说明】 本研究针对源自绿藻的硫酸化多糖ulvan（Ulvan）相关出版物开展荟萃分析。相关文献于2017年12月13日从Web of Science核心合集（Web of Science Core Collection）与Scopus数据库中检索得到，检索式为："(Ulvan* OR ((sulfate* OR sulphate*) AND polysaccharide* AND (Ulva OR Enteromorpha)))"。仅符合以下标准的文献方可纳入荟萃分析表格：其一，研究需使用石莼属（Ulva）或浒苔属（Enteromorpha）藻类，并涉及硫酸化多糖的提取；其二，需为硫酸化多糖的提取、表征及/或应用提供原始定量数据。本荟萃分析共纳入154篇文献，对每篇文献均提取以下数据：(1) 发表年份、第一作者、标题前40个字符、刊载期刊；(2) 研究所用藻类的属、种信息，生物质来源的国家及相关描述；(3) 所使用的提取剂及其浓度（如适用）、所用酶类、提取温度与时长，以及是否使用沉淀剂及沉淀剂种类；(4) 多糖得率（干重百分比% DW）、总碳水化合物、蛋白质、灰分、硫酸盐、糖醛酸及中性糖含量（均以重量百分比w/w计）；(5) 平均分子量；(6) 单糖组成，包括鼠李糖、糖醛酸、葡萄糖醛酸、木糖、艾杜糖醛酸、葡萄糖及半乳糖的含量（以摩尔百分比% Mol、干重百分比% DW或摩尔比计）；(7) 用于评估提取多糖生物医学应用的检测方法。数据将按照原文呈现的形式与单位进行记录，仅当仅需调整数值量级以保证表格内数据具有可比性时，才进行单位转换。若执行了单位转换，对应单元格将以虚线标注，且可通过阅读对应公式了解具体转换规则。部分数据从图表中估算得到，此类数值同样以虚线标注。若文献提供的数据单位与表格所用单位不一致，则将此类数据以带对应单位的文本形式录入，避免其被纳入荟萃分析的数值统计。