Summary of receptor and CEA molecules, GFP expression and oncolytic effect mediated by RCAd11pGFP.

Note: Geometric mean was used to compare the amounts of CD46, avb3, avb5, and CEA molecules expressed on the different cell surfaces.*: 7,000 vp/cell gave 36% GFP-expressing cells. **: 7,000 vp/cell gave 41% GFP-expressing cells.***: Ratio (fold) of cell lysis to transduction means the ratio of the cytolytic effect of the amount of RCAd11pGFP virus particles (vp) required to obtain 50% cell lysis at 12 days p.i. to the transduction efficiency of the vector (vp) required to obtain 50% GFP-expressing cells at 24 h p.i. This ratio was compared in each colon carcinoma cell line. The results are presented as the mean value of three independent experiments. A549 cells were used as the control cell line.