Related Article from Test-Firing Ammunition for Spliceosome Inhibition in Cancer

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https://figshare.com/articles/dataset/Related_Article_from_Test-Firing_Ammunition_for_Spliceosome_Inhibition_in_Cancer/22451730 数据链接链接失效反馈

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Related Article from Test-Firing Ammunition for Spliceosome Inhibition in Cancer

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2013-11-15

美国国家癌症研究所癌症研究数据

癌症药物开发

肿瘤分子机制研究

美国国家癌症研究所癌症治疗与诊断部（Division of Cancer Treatment and Diagnosis，DCTD）建设的癌症研究数据资源汇总入口，集中提供可公开检索或下载的抗癌药物筛选、化合物与化学结构、NCI-60 肿瘤细胞系分子特征、蛋白质组学、医学影像和遗传变异等数据。平台整合 NCI-60 生长抑制数据、体内抗肿瘤实验数据、Proteomic Data Commons、T

知名数据库100

Lentiviral-based mutagenesis to identify mutations that confer resistance to anti-cancer drugs [lenti]

抗癌药物耐药突变鉴定

癌症药物开发

Identifying resistance mutations in a drug target provides crucial information. Lentiviral transduction creates multiple types of mutations due to the error-prone nature of the HIV-1 reverse transcrip

NIAID Data Ecosystem60

Microarray analysis of isoginkgetin-treated HCT116 and HCT116p53-/- cells. Microarray analysis of isoginkgetin-treated HCT116 and HCT116p53-/- cells

剪接体抑制

ATF4应激通路

Isoginkgetin (IGG) is a small molecule inhibitor of the spliceosome although the direct target remains elusive. Widespread failure to accurately remove introns poses a risk to cells and organisms thro

NIAID Data Ecosystem40

In Vivo Activity and Pharmacokinetics of Nemorosone on Pancreatic Cancer Xenografts

癌症药物开发

抗癌化合物

Pancreatic cancer is one of the leading cancer-related causes of death in the western world with an urgent need for new treatment strategies. Recently, hyperforin and nemorosone have been described as

NIAID Data Ecosystem70

The Development of Hsp90β-Selective Inhibitors to Overcome Detriments Associated with pan -Hsp90 Inhibition

Hsp90亚型选择性抑制

癌症药物开发

The 90 kD heat shock proteins (Hsp90) are molecular chaperones that are responsible for the folding of select proteins, many of which are directly associated with cancer progression. Consequently, inh

NIAID Data Ecosystem50

Related Article from Test-Firing Ammunition for Spliceosome Inhibition in Cancer

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