Next Generation Sequencing of Pkd1 mutant kidneys

This study sough to understand the differential gene expression profile of Pkd1 mutant mice kidneys in the setting of miR 17~92 deletion 3 Pkd1 knockout mice and 3 Pkd1 miR-17 knockout mice were analyzed本研究旨在探究miR-17~92（miR 17~92）缺失背景下Pkd1突变小鼠的肾脏差异基因表达谱。共分析了3只Pkd1单敲除小鼠与3只Pkd1联合miR-17~92敲除小鼠。