Progenitor cells of yolk sac and bone marrow origin were transduced with an estrogen receptor Hoxb8 fusion protein to generate stable cell lines. Macrophages were differentiated with M-CSF in the abse
Changes in gene regulation have long been known to play important roles in both innate and adaptive immune responses. However, post-transcriptional mechanisms involved in mRNA processing have been poo
Vibrio vulnificus is a marine zoonotic pathogen associated with fish farms that is considered a biomarker of climate change. Zoonotic strains trigger a rapid death of their susceptible hosts (fish or
OT-1 cells were adoptively transferred to naive animals which were subsequently immunized with MCMV-SIINFEKL or RAE-1gMCMV-SIINFEKL viral vectors. On day 36 OT-1 cells were sorted using FACS and RNA w
Purpose: The goals of this study were to identify molecular patterns activated by the vaccine and potential predictors of clinical success. Methods: Whole blood samples (2.5 ml) were collected into PA
