Grape seed proanthocyanidins alter microbiota and enterohormone secretions after 8 days of treatment in rats. URV_GSPE_study

Grape seed proanthocyanidin extract (GSPE) modulates several parameters involved in metabolic syndrome. GSPE is a mixture of compounds, some of which are rapidly absorbed, but others remain in the lumen where they might have some effects that are translated to the whole organism. Our aim is to decipher if an 8-day treatment with GSPE, previously shown to reduce food intake, induces changes in the microbiota and enterohormone secretion.