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Effects of thyroid hormone on human preimplantation embryos

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE131488
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We found that the exposure of human preimplantation embryos to triiodothyronine (T3) has a profound impact on gene transcription only in the cells of inner cell mass (ICM) and no effect on cells of trophectoderm (TE). A total of 30 embryos at the two pronuclear (2PN) stage were used for the experiment; fifteen embryos were exposed to 10-7 M T3 till blastocyst stage and the remaining 15 embryos acted as controls.
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2022-05-20
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