CosMx 6175 human gene for human kidney primary non-function and immediate graft function.. CosMx 6175 human gene for human kidney primary non-function and immediate graft function.

This dataset includes CosMx spatial transcriptomic data from human kidney biopsies collected one hour post-transplantation. Patients were then monitored and categorized into two groups: immediate graft function (IGF) and primary nonfunction (PNF). PNF refers to cases where the transplanted kidney never functions. The biopsies were formalin-fixed, paraffin-embedded, and sectioned using a microtome. Sample processing followed NanoString's standard protocol, utilizing a pre-made 6,175-gene panel to detect the spatial location and expression levels of each gene, without any additional custom probes. Overall design: This study contains human kidney biopsies form 2 groups: immediate graft function (IGF) and those with delayed graft function (PNF).