five

Immune cell transcriptional programs severe allergic airway inflammation

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP464508
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Innate and adpative immune cells play an integral role in asthma pathogenesis. We performed single cell RNA sequencing on CD45+ immune cells isolated from PBS or c-di-GMP + mixed allergen challenged mice. Overall design: CD45+ cell were isolated from the mouse lung following intranasal PBS or c-di-GMP + mixed allergen exposures 3X per week for 7 weeks. Two mouse lungs given the same treatments were pooled following digestion.
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2024-05-01
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