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DGAT1 is a bona fide oncogene stimulating cell growth and suppressing oxidative stress while enabling fatty acid accumulation

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144555
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Forced over-expression of dgat1a using the minicoopR system increased the rate of tumour formation in tp53m214K/m214k; mitfa-/-; nras G12D. This was through increased TOR signalling and alterations in key metabolic pathways. Examination of the effect of dgat1a overexpression in NRAS driven Zebrafish Melanoma using the miniCoopR system.
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2023-01-30
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