Interaction of integrin alphaVbeta3 with Tenascin

Tenascin, an extracellular matrix protein acts as a ligand to multiple integrin receptors including alphaVbeta3. Integrin alphaVbeta3 binds to the third fibronectin type III repeat in tenascin (Tnfn3) and induces the cell proliferation.

Tenascin，一种细胞外基质蛋白，充当多种整合素受体的配体，包括alphaVbeta3。整合素alphaVbeta3与Tenascin（Tnfn3）中的第三种纤连蛋白III型重复序列结合，并诱导细胞增殖。