LCA and PCN activate different target genes, but markedly overlapping GO biological processes.
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Quadruplicate cultures of primary rate hepatocytes were exposed to PCN or LCA for 48 hours. RNA was extracted and gene expression monitored using Affymetrix rat 230 v2 microarrays. Gene expression number relates to those identified as significantly altered via SAM analysis; functional annotation clustering was undertaken on these identified genes using DAVID, with GO biological process 3–5 as the search term.
创建时间：
2011-02-02
