Methods and data related to the publication " Safety and growth promoting potential of repeated administration of sodium salicylate to broilers "

This file is part of "Methods and data related to the publication " Safety and growth promoting potential of repeated administration of sodium salicylate to broilers "". The data presented here refer to the study of the inclusion of the non-steroidal anti-inflammatory sodium salicylate in the diet of male broilers of the Cobb 500 strain, during 42 days of life. The objective of this work was to evaluate the possible adverse effects of the prolonged consumption of this drug, as well as to evaluate the improvement in the zootechnical indices of these animals, such as increased weight gain and improved feed conversion. The data obtained were statistically evaluated using the SAS/STAT software program (SAS Institute, Cary, NC, USA) with the alpha value set to 0.05. Linear and quadratic polynomial contrasts were specified for dose-response modeling with correction for unequal spacing of SS doses, namely 0, 2.5, 5.0, and 10.0 mg/kg per day. Data subject with repeated measurements (BW, BWG, FI, FC) from the same individuals over a period of time were subjected to the linear mixed model, with treatment, time and the treatment x time interaction as fixed effects (available as supplemental material). The results were positive regarding possible adverse effects, showing that there was no toxicity to the animals at the doses used. However, there was no statistically significant improvement in broiler weight gain, but there was a non-statistical increase in the group treated with the highest dose. Because of this, further investigations must be carried out.