Metabolic maturation of neonatal hearts driven by gamma-linolenic acid in maternal milk [RNA-seq]

The goal of this study was to compare the transcriptome profile (RNA-seq) of perinatal hearts of cardiomyocyte-specific RXRab-deficient (edKO) and WT mice, to identify genes that are controlled by the expression of the TF RXRa and RXRb. Hearts from wild type (WT) and cardiomyocyte-specific RXRab-/- (edKO) P0 newborns were collected and analyzed by RNASeq.本研究旨在对比心肌细胞特异性RXRab缺陷型（edKO）与野生型（Wild Type，WT）小鼠围产期心脏的转录组谱（RNA-seq），以鉴定受转录因子（Transcription Factor，TF）RXRα和RXRβ表达调控的基因。研究收集了野生型（WT）及心肌细胞特异性RXRab缺陷型（edKO）的P0新生小鼠心脏，并通过RNA测序（RNA-seq）完成分析。