RNA-seq data of sistl1 and Yugu1

NIAID Data Ecosystem2026-03-10 收录

DNA复制基因表达调控

细胞周期S期调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/ERP107661 数据链接链接失效反馈

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资源简介：

expressions of genes variously involved in the assembly and activation of the DNA pre-replicative complex, elongation of replication forks and S phase entry are reduced in sistl1.

创建时间：

2018-07-03

Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease

"组蛋白mRNA3端加工"

细胞周期S期调控

During S-phase of the cell cycle production of the core histone proteins is precisely balanced with DNA replication. Metazoan mRNAs encoding replication dependent (RD) histones lack polyA tail normall

NIAID Data Ecosystem40

E2F7 represses a transcriptional network of oscillating cell cycle genes to control S-phase progression.

细胞周期S期调控

E2F7转录因子靶基因

E2F transcription factors are known to be important for timely activation of G1/S and G2/M genes required for cell cycle progression, but transcriptional mechanisms for deactivation of cell cycle regu

NIAID Data Ecosystem40

Transcriptional profiling of MLL5 Knock down vs. control C2C12 myoblasts (S phase enriched)

MLL5基因功能

细胞周期S期调控

Knockdown of MLL5 led to deregulation of S phase. To understand the molecular basis for this phenotype, we performed microarray analysis of S phase synchronized myoblasts. Genes differentially regulat

NIAID Data Ecosystem10

S Phase Progression in Human Cells Is Dictated by the Genetic Continuity of DNA Foci

DNA复制时序

细胞周期S期调控

DNA synthesis must be performed with extreme precision to maintain genomic integrity. In mammalian cells, different genomic regions are replicated at defined times, perhaps to preserve epigenetic info

NIAID Data Ecosystem40

Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing dynamics

复制起始点激活动力学

细胞周期S期调控

Genome stability requires complete DNA duplication exactly once before division. In eukaryotes, cyclin-dependent kinase (CDK) plays a dual role in this regulation by inhibiting helicase loading factor

NIAID Data Ecosystem30

RNA-seq data of sistl1 and Yugu1

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