Allen Institute - Visual Coding - Optical Physiology

From the Allen Institute Brain Observatory, the Visual Coding (optical physiology) dataset is a large-scale, standardized survey of physiological activity across the mouse visual cortex, hippocampus, and thalamus. This two-photon imaging dataset features visually evoked calcium responses from GCaMP6-expressing neurons in a range of cortical layers, visual areas, and Cre lines. We hope that experimentalists and modelers will use these comprehensive, open datasets as a testbed for theories of visual information processing. Full documentation of the Visual Coding Ophys dataset and tutorials can be found here: https://observatory.brain-map.org/visualcoding/ The Visual Coding Ecephys (NeuroPixels) dataset can be found here: https://dandiarchive.org/dandiset/000021

搜集汇总

背景与挑战

背景概述

该数据集由Allen Institute提供，是视觉编码（光学生理学）项目的一部分，使用双光子钙成像技术记录小鼠视觉皮层、海马体和丘脑中GCaMP6表达神经元对视觉刺激的钙响应，涵盖271只小鼠的多种皮层层次、视觉区域和Cre品系，数据以NWB格式存储，开放获取（CC-BY-4.0）。