The PSA-/lo prostate cancer cells harbor self-renewing long-term tumor-propagating cells that resist castration

NIAID Data Ecosystem2026-03-11 收录

去势抵抗性前列腺癌

肿瘤干细胞

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE35814 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-07-30

Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer. Systematic characterization of epigenetic modifying enzymes identifies KDM3B as a key regulator in castration resistant prostate cancer

去势抵抗性前列腺癌

表观遗传靶点

Androgen deprivation therapy (ADT) is the standard care for prostate cancer patients who fail surgery and radiotherapy. While initially effective, the cancer almost always recurs into a more aggressiv

NIAID Data Ecosystem100

Phenotypic characterization of two novel cell line models of castration resistant prostate cancer

去势抵抗性前列腺癌

癌症耐药机制研究

Purpose: Resistance to androgen deprivation therapies is a major driver of mortality in advanced prostate cancer. Therefore, there is a need to develop new pre-clinical models that allow the investiga

NIAID Data Ecosystem50

Supplementary Table 1. Sequence Data for mRNAs in CD133(+) cells compared with CD133(-) cells from Saos-2 cell line..xlsx

基因表达

肿瘤干细胞

Sequence Data for mRNAs in CD133(+) cells compared with CD133(-) cells from Saos-2 cell line..xlsx

DataCite Commons2022-03-31 更新50

Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

单细胞表观遗传学

去势抵抗性前列腺癌

Understanding prostate response to castration and androgen receptor signaling inhibitors (ARSI) is critical to improving long-term prostate cancer (PCa) patient survival. We use a multi-omics approach

NIAID Data Ecosystem100

ARv7 represses tumor suppressors genes in castration-resistant prostate cancer [RNA-Seq]

去势抵抗性前列腺癌

转录抑制机制

Endocrine therapies in prostate cancer (PCa) treatment block androgen receptor (AR) function, but are palliative as tumors progress to a lethal, castration-resistant state (CRPC). CRPC remains depende

NIAID Data Ecosystem50

The PSA-/lo prostate cancer cells harbor self-renewing long-term tumor-propagating cells that resist castration

资源简介：

相关数据集