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Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma

NIAID Data Ecosystem2026-05-02 收录

滑膜肉瘤转录组

SUMO化修饰

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE266135 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-08-07

SUMO化修饰

非整倍体机制

Post-translational protein modification by the small ubiquitin-related modifier (SUMO) protein regulates numerous cellular pathways, including transcription, cell division and genome maintenance. The

NIAID Data Ecosystem100

Table_5_High Migration and Invasion Ability of PGCCs and Their Daughter Cells Associated With the Nuclear Localization of S100A10 Modified by SUMOylation.DOCX

肿瘤细胞迁移与侵袭机制

SUMO化修饰

Our previous studies have confirmed that cobalt chloride (CoCl2) or chemoradiotherapy could induce the formation of polyploid tumor giant cells (PGCCs). Polyploid giant cancer cells are a special subp

NIAID Data Ecosystem60

DataSet_synovial_sarcoma_RNA - samples

滑膜肉瘤转录组

肿瘤基因测序

Rare cancer sequencing data of 23 runs in tumor/control pairs, which were uploaded to umbrella studies. The sequencing was always pairedEGA dataset EGAD00001008844

NIAID Data Ecosystem50

Proteomes of chromatin fractions derived from SU-DHL-5 cells

染色质蛋白

SUMO化修饰

SU-DHL-5 cells display limited expression of the SUMO isopeptidase SENP6. In this experiment, the chromatin associated fraction of SU-DHL-5 cells was analysed by mass spectrometry. SU-DHL-5 cells were

NIAID Data Ecosystem100

SENP3-mediated host defense response contains HBV replication and restores protein synthesis

乙型肝炎病毒

SUMO化修饰

Certain organs are capable of containing the replication of various types of viruses. In the liver, infection of Hepatitis B virus (HBV), the etiological factor of Hepatitis B and hepatocellular carci

NIAID Data Ecosystem50

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma

资源简介：

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