Crystal Structure of the first bromodomain of human BRD4 BD1 in complex with the inhibitor Y13221
收藏Protein Data Bank Japan2024-12-25 更新2026-06-30 收录
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Crystal Structure of the first bromodomain of human BRD4 BD1 in complex with the inhibitor Y13221 Descriptor: 2-[2-ethyl-4-(methoxymethyl)-1~{H}-imidazol-5-yl]-7-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-5-methyl-furo[3,2-c]pyridin-4-one, BRD4_HUMAN Authors: Li, J, Hu, Q, Xu, H, Zhao, X, Zhang, C, Zhu, R, Wu, X, Zhang, Y, Xu, Y. Deposit date: 2024-05-22 Release date: 2024-12-11 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (3 Å) Cite: Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors. J.Med.Chem., 67, 2024
创建时间：
2024-05-22
