RNA-Sequencing of Acute interstitial pneumonia compared with Control Lung

Acute Interstitial Pneumonia (AIP) represents a severe form of diffuse lung injury within the idiopathic interstitial pneumonia spectrum. Given the limited understanding of its molecular basis, this study aims to elucidate AIP's transcriptomic profiles to uncover its pathophysiological underpinnings and identify potential therapeutic targets. To determine the common and unique molecular features of AIP, transcriptome analysis of lung samples from AIP (N=15), controls (N=5) was conducted. Differential gene expression was determined using p-value to control for comparison.