Raw data for figure preparation, supplemental files, and supplemental figures: POLD1-based resistance in diverse species
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Figure 1 data: all input text files and R code to create panels A-D of Figure 1; 1 sub folder for each speciesFigure 2 data: all input text files and R code to create panels A & B of Figure 2Supplemental_Figures: Figure S1, S2, S3Supplemental File 1: contains the alignment of each species of interest to cassava POLD1 and the custom perl script used to identify mutation coordinates in cassava POLD1 sequence.Supplemental File 2: The multiple sequence alignment of POLD sequences generated by SIFT for evaluation of mutations on protein function. QUERY: Manes.12G077400; Q9LRE6: Oryza sativa subsp. japonica (Rice); O48901: Glycine max (soybean); Q9LVN7: Arabidopsis thaliana; O54747: Rattus norvegicus (rat); P97283: Mesocricetus auratus (golden hamster); P28339: Bos taurus (bovine); P28340: Homo sapiens (human); P30316: Schizosaccharomyces pombe (fission yeast); Q54N97: Dictyostelium discoideum (social amoeba); P54358: Drosophila melanogaster (fruit fly); P46588: Candida albicans (yeast); P15436: Saccharomyces cerevisiae (baker’s yeast); P90829: Caenorhabditis elegans (nematode); P30315: Plasmodium falciparum; P30315: Paramecium bursaria Chlorella virus NY2A.Supplemental File 3: MP4 movie generated from Chimera showing the POLD1 3D structure from H. sapiens (6NTZ); residues identified in this study are highlighted according to the legend in Fig. 3.Supplemental_File_Descriptions: contains the legends for the Supplemental Files listed above
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2025-09-09



