Double Lawton S<sub>N</sub>2‘Addition to Epoxyvinyl Sulfones: Selective Construction of the Stereotetrads of Aplyronine A<sup>†</sup>
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Enantiopure epoxyvinyl sulfones function as templates for the diastereoselective construction of the three stereotetrads of aplyronine A. Lawton SN2‘ addition of 3,5-dimethylpyrazole followed by its displacement in an alcohol-directed Lawton SN2‘ reaction establishes the required product stereochemistry with high selectivity.
创建时间：
2016-03-01
