List of the candidate genes found for 81 OMIM loci with unknown molecular basis.

The column ��status�� reviews the current knowledge about the association of the candidate with the disease. In particular, 1 = gene not previously associated with the disease; 2 = gene involved in mendelian phenotype sharing a MimMiner similarity score of 0.4 or higher with the phenotypic description of the locus; 3 = gene previously considered as a candidate for clinical similarity, but with a MimMiner similarity score to the locus lower than 0.4. Moreover, genes annotated with ��#�� represent the actual disease gene, because mutations have been found in patients; genes annotated with ���ꡱ have been excluded by refining the map interval; genes annotated with ��*�� could be excluded because mutations have been found in a different gene of the same locus; genes annotated with ��$�� are at the moment excluded because they have been screened but no mutations considered to be relevant have been found. The above statements are supported by the indicated references: i = [38]; ii = [39]; iii = [40]; iv = [41]; v = [42]; vi = [43]; vii = [44]; viii = [45]; ix = [46]; x = [47]; xi = [48]; xii = [49]. The column ��Net.�� indicates the networks from which the candidate was predicted: A = Affy; S = Stanford.