Aurora A ligand complex

Aurora A ligand complex Descriptor: (2S,4R)-1-[(3-chloro-2-fluorophenyl)methyl]-2-methyl-4-({3-[(1,3-thiazol-2-yl)amino]isoquinolin-1-yl}methyl)piperidine-4-carboxylic acid, Aurora kinase A, DIMETHYL SULFOXIDE, ... Authors: Antonysamy, S, Pustilnik, A, Manglicmot, D, Froning, K, Weichert, K, Wasserman, S. Deposit date: 2018-01-08 Release date: 2019-01-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of theRB1Tumor Suppressor Gene. Cancer Discov, 9, 2019极光激酶A配体复合物（Aurora A ligand complex）描述符：(2S,4R)-1-[(3-氯-2-氟苯基)甲基]-2-甲基-4-({3-[(1,3-噻唑-2-基)氨基]异喹啉-1-基}甲基)哌啶-4-羧酸、极光激酶A（Aurora kinase A）、二甲基亚砜（DIMETHYL SULFOXIDE）等。作者：Antonysamy S、Pustilnik A、Manglicmot D、Froning K、Weichert K、Wasserman S。入库日期：2018-01-08；发布日期：2019-01-23；最后修改日期：2024-03-13。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.73埃。引用文献：《Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene》，刊载于《Cancer Discov》第9卷，2019年。