Additional file 2 of Reduction of alternative polarization of macrophages by short-term activated hepatic stellate cell-derived small extracellular vesicles
The goal of this experiment was to identify the differential expression of microRNAs in human polarised macrophages. We used monocyte-derived macrophages isolated from 8 different healthy invididuals.
The Notch pathway plays critical roles in the development and functional modulation of myeloid cells. Previous studies have demonstrated that Notch activation promotes M1 polarization and phagocytosis
In previous study, we found TTF could regulate M2 polarization in the atherosclerotic plaque in ApoE-/- mice, but the underlying mechanism remains unknown. To detect the effect of TTF on RNA expressio
Our previous study found that lipoxin A4 (LXA4) exerted therapeutic effects on osteoarthritis (OA). In this study, we evaluated the effects of LXA4 via synovial macrophage M1/M2 subtype polarization o