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FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy [human_FOXO1_scRNAseq]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263256
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gene expression profile of human FOXO1overexpressing α-lewisY CAR T cells on single cell level Human anti-Lewis Y CAR T cells overexpressing mCherry (control) or FOXO1 were generated from healthy donor peripheral blood mononuclear cells (PBMC). Control or FOXO1 overexpressing CD8+ CAR T cells were non-stimulated or stimulated with MCF7 tumour cells for 24 hours and assessed by scRNA-Sequencing
创建时间:
2024-05-09
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