Role of PMS1 in MMR events occurring across the yeast nuclear genome
收藏NIAID Data Ecosystem2026-05-01 收录
官方服务:
资源简介:
The aim of this work was to study genomic instability
应用场景:
创建时间:
2024-03-13
相关数据集
Additional file 2 of Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses
Additional file 2. Contains CNAs for RPE1 after treatment with DMSO, Aphidicolin or siRNA.
NIAID Data Ecosystem110
Hemizygous loss of helicases promotes genomic instability and cancer development
Cancer mutations perturb key processes, leading to uncontrolled cell proliferation. With the pivotal and specific roles for enzymes at all levels of cellular function and growth, we hypothesized that
DataONE2025-12-19 更新50
Cohesin maintains replication timing to suppress DNA damage on cancer genes [MCM5_ChIPseq]
Cohesin loss-of-function mutations are frequently observed in tumors, but the mechanism is unclear. Here, we found that depletion of RAD21, a core subunit of cohesin, leads to massive genome-wide DNA
NIAID Data Ecosystem30
File S1 - Microsatellite Stable Colorectal Cancers Stratified by the BRAF V600E Mutation Show Distinct Patterns of Chromosomal Instability
Contains the files: Figure S1. Automatic inclusion of cancer samples with tumour percentage ≥40% as estimated by SiDCoN. Figure S2. Frequency of copy number aberrations occurring delineated by their f
Figshare2015-12-02 更新60
Drosophila salivary gland imaginal ring tumor single cell DNA copy number variation (CNV)
Variation and heterogeneity in ploidy are general features of human cancers. This variation can be an increase of the number of chromosome set (polyploidy), an increase or decrease of a small numbers
NIAID Data Ecosystem40



