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Transcriptome Profiling of Neutrophils from Patients Infected with IAV using RNA-seq

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108807
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Purpose: To explore the roles of host lncRNAs during IAV infection Methods:profiling whole transcriptional alterations using RNA-seq in neutrophil samples from 3 patients infected with IAV in the acute stage and their matched recovery-stage samples Results:We identified a total of 404 differentially expressed genes (FC>2, p<0.05), including 234 up-regulated and 170 down-regulated genes,in each patient sample Conclusion:Our study is the first profile of the transcriptome of IAV-infected patients' neutrophils The transcriptome profile of IAV-infected patients' neutrophils in the acute stage and recovery stage were generated by deep sequencing using Illumina Illumina HiSeq 2000
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2023-09-08
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