Baseline characteristics by presence of a tobacco stain on fingers.

* Chi-squared test or the Fisher exact test† Wilcoxon rank sum test‡ Number of packs smoked in a day multiplied by the number of years spent smoking or sum of the different PYs throughout life if the consumption was higher or lower for more than a year’s duration.§ Vascular disease is composed from any of ischemic heart disease, stroke, or peripheral vascular disease.|| Harmful alcohol use: high alcohol intake associated with documented withdrawal or medical consequences. IQR: interquartile range 25–75%Baseline characteristics by presence of a tobacco stain on fingers.