首页/数据集/ORP2, a cholesterol transporter, regulates angiogenic signaling in endothelial cells

ORP2, a cholesterol transporter, regulates angiogenic signaling in endothelial cells

NIAID Data Ecosystem2026-03-12 收录

血管生成机制

细胞信号转导

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP295215 数据链接链接失效反馈

官方服务：

资源简介：

This study investigated the role of ORP2 in endothelial cell EC cholesterol and PI4,5P2 distribution, angiogenic signaling, and angiogenesis, by transient knock-down of ORP2

应用场景：

创建时间：

2020-12-04

血管血流感应机制

细胞信号转导

GPR68 is an essential flow sensor in arteriolar endothelium, and is a critical signaling component in cardiovascular pathophysiology RNAseq of cells from mesenteric endothelium of mice plus and minus

NIAID Data Ecosystem80

Long Non-Coding RNA MEG3 Promotes Angiogenesis by directly regulating integrin signaling impairing endothelial cell function [ChIP-seq]

非编码RNA功能

血管生成机制

We immunoprecipitated EZH2, together with associated chromatin isolated from the HUVECs (2 x 10^6) that were transfected with MEG3 GapmeRs (10 nM, 48 h) or a scrambled control GapmeRs (Ctr). For trans

NIAID Data Ecosystem60

Effects of concentrated growth factors on the angiogenic properties of dental pulp cells and endothelial cells: an in vitro study

牙髓再生

血管生成机制

Abstract The aim was to investigate the angiogenic effects of concentrated growth factors on human dental pulp cells and human umbilical vein endothelial cells. Cells were treated with concentrated gr

Figshare2018-06-01 更新30

A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression. A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression

炎症基因表达

细胞信号转导

BMDMs were generated via differentiation of bone marrow cells in culture media containing m-CSF for 7 day. Upon differentiation, BMDMs were left untreated or stimulated with LPS, IFNa, PGE2, LPS+PGE2,

NIAID Data Ecosystem70

The B-Raf Status of Tumor Cells May Be a Significant Determinant of Both Antitumor and Anti-Angiogenic Effects of Pazopanib in Xenograft Tumor Models

肿瘤药物靶点研究

血管生成机制

Pazopanib is an FDA approved Vascular Endothelial Growth Factor Receptor inhibitor. We previously reported that it also inhibits tumor cell B-Raf activity in an experimental brain metastatic setting.

NIAID Data Ecosystem50

ORP2, a cholesterol transporter, regulates angiogenic signaling in endothelial cells

资源简介：

相关数据集