An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer: DNA methylation. Homo sapiens

Methylation profiles of a panel of breast cancer lines that were included in the integrative analysis of DNA copy number, allelic status, DNA methylation and gene expression. Overall design: Methylation profiles of 9 breast cancer cell lines and one normal line were generated. Genes were determined to be hyper and hypomethylation in a cell line with respect to the normal line, MCF10A.