Parameters of the model (FOXO synthesis/degradation and PTM addition/removal processes).

Rate constants of FOXO synthesis/degradation and PTM addition/removal processes. For a given process, the first-order rate constant is given, and, for enzyme catalysed reactions, a derived second-order constant and the putative enzyme molecule number that produced it. Only the product of these, the first order constant, is related to experimental measurements. Where appropriate, a list is then given of a series of multiplicative factors (MFs) which may modify the rate for the process, depending on the presence of a another particular PTM in the FOXO species.