p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18
收藏reactome.org2025-01-09 收录
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FUNDC1-mediated mitophagy is inhibited by its phosphorylation at the Tyr 18 position in the LIR motif by Src kinase under normoxia conditions. These phosphorylation events insure that FUNDC1 cannot bind LC3.
在正常氧压条件下，由Src激酶介导的Tyr 18位点上磷酸化作用抑制了FUNDC1介导的线粒体自噬，这些磷酸化事件确保了FUNDC1无法与LC3结合。
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