Proportion of women represented in recent AF clinical trials versus the SAFETY cohort.

SAFETY = Standard versus Atrial Fibrillation spEcific managemenT study.ARISTOTLE = Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation Study.AVERROES = Apixaban Versus Acetylsalicylic Acid to Prevent Stroke in Atrial Fibrillation Patients Who Have Failed or Are Unsuitable for Vitamin K Antagonist Treatment.ROCKET-AF = Rivaroxaban Once daily oral direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation).RACE = RAte Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study.RE-LY = Randomised Evaluation of Long term anticoagulant therapy.AFFIRM = Atrial Fibrillation Follow-up Investigation of Rhythm Management.