Effects of different amoxicillin treatment durations on gut microbiomes

In this study the objective is to investigate effects of standard and reduced antibiotic treatment lengths on gut microbiomes using a murine model. Changes in the murine gut microbiome will be assessed after using three different treatment durations of amoxicillin (3, 7 or 14 days) as well as a control group not receiving amoxicillin. Fecal samples will be collected before and during the whole experiment, until three weeks past end of treatment. These will further be subject for 16S rRNA Illumina MiSeq sequencing. The sequencing results will be used to demonstrate alterations in bacterial diversity, richness and evenness during and after amoxicillin treatment of various temporal length.