Based on RNA-SEQ and experimental validation to explore the similarities and differences in catabolism and proliferation of chondrocyte inflammatory models between rats and mice.

IL-1β promotes the proliferation of rat chondrocytes and inhibits the proliferation of mouse chondrocytes.白细胞介素1β（IL-1β）可促进大鼠软骨细胞的增殖，并抑制小鼠软骨细胞的增殖。