Expanded B cell clone in the cerebrospinal fluid of a patient with GABAA-R encephalitis
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https://www.ncbi.nlm.nih.gov/sra/SRP267951
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资源简介:
Encephalitis associated with antibodies against the neuronal gamma-aminobutyric-acid-A receptor (GABAA-R) is a rare form of autoimmune encephalitis. The pathogenesis is still unknown but autoimmune mechanisms were surmised. Here we identified a strongly expanded B cell clone in the cerebrospinal fluid of a patient with GABAA-R encephalitis. We expressed the antibody produced by it, and showed by ELISA and immunohistochemistry that it recognizes the GABAA-R.
创建时间:
2021-07-01



